QUEL Imaging awarded Phase I SBIR grant
QUEL Imaging LLC was awarded a grant by the National Institutes of Health for just over a quarter of a million US dollars. The concept for the grant funded by the NIBIB, stems from work in Ruiz’s studies developing 3D printed test targets for surgical system calibration. Read the full Press Release.
Ruiz is first author of publication describing fluorescence phantom development
With the growing adoption of fluorescence guided surgery using indocyanine green (ICG), there stands a need to characterize performance of various imaging systems. This paper describes a method of developing a solid ICG-equivalent reference phantom with long-term stability. Read more in this JBO publication.
Getting to know our CEO, Ethan LaRochelle
The Thayer School of Engineering at Dartmouth produces a video series called “I’m an Engineer and…”. In the latest edition they interview Ethan LaRochelle about his volunteer experience. Watch the video here.
LaRochelle defends his thesis over Zoom
Due to COVID-19 Ethan LaRochelle presented his thesis, “Modeling broad-spectrum light sources in vivo for applications in cancer treatment & diagnostics” from his home in Vermont. While non-traditional, this allowed for collaborators and participants from outside the Dartmouth community to easily join. A recording is available on YouTube.
LaRochelle’s submission featured on cover of March/April issue of Photochemistry and Photobiology
The dose modeling work highlighted in Photochemistry and Photobiology was selected to submit a cover image to the March/April issue. See the cover here.
Ruiz presents work at SPIE BIOS on developing characterization tools for fluorescence-guided imaging
One method QUEL Imaging aims to provide support for the field of optical surgical systems is through the development of innovative tools. Alberto Ruiz presented at SPIE BIOS on work describing the development and characterization of fluorescence phantoms. The founding members of QUEL Imaging also met with many in this industry during the conference, and presented on many other tangential topics.
Scottish Photobiology Unit highlights LaRochelle’s daylight dose model
Researchers at the Photobiology Unit of Ninewells Hospital in Dundee, Scotland described their experiences using the dose model for indoor daylight PDT. In a Highlight Article published in Photochemistry and Photobiology they describe the process as “very easy” obtaining results with the confidence intervals even as their measurements were performed on the other side of the Atlantic Ocean. Read more about their experience.
Ruiz has paper describing smartphone-based fluorescence imaging accepted to the Journal of Biomedical Optics
The dynamics of how the photosensitizer PpIX develops in skin lesions may help dermatologists tailor PDT treatments. Up until recently quantitative measurements required expensive bench-top equipment, but in this paper Ruiz describes how a smartphone can be used with a clip-on module to measure PpIX during PDT treatments of skin. Read the full paper here.
An interview with our President, Brian Pogue
The Magnuson Center for Entrepreneurship recently wrote about Brian Pogue’s experiences bringing biotech innovations to the market. Read more from his interview here.
QUEL Imaging awarded seed funding through the Quinn Innovation Scholars program
The founding members of QUEL Imaging pitched their idea for planning and monitoring daylight-activated photodynamic therapy of skin lesions using a smartphone. This competitive pitch process was reviewed by a board of advisors from the Norris Cotton Cancer Center and Tuck School of Business, among others. With the $20K in seed funding QUEL Imaging will further develop and test a prototype system.
LaRochelle publishes article on using weather for dose planning indoor daylight PDT of skin
Photochemistry and Photobiology published a research paper describing how complex Monte Carlo models of light fluence at depth in tissue could be simplified and combined with a site assessment and weather reports to estimate the photodynamic dose received by patients undergoing PDT treatments for skin lesions such as actinic keratosis. Read the full paper here.
LaRochelle and Ruiz present at the 17th International Photodynamic Association World Congress
Both Ethan LaRochelle and Alberto Ruiz presented in a session on Low-Cost Systems and Techniques in PDT Light Deliver, Dosimetry, and Treatment Guidance. Ruiz, gave an invited talk on smartphone-based dosimetry for individualization of PDT treatment planning, and LaRochelle presented the concept of using weather forecasts and light-tissue models for daylight PDT treatment planning.